Which drug is better utrogestan or duphaston. The composition of Duphaston and Utrozhestan and the release form

Hormonal preparations to maintain pregnancy

Doctors know that almost no pregnancy is complete without prescribing at least some pills. And even if we are talking about "harmless" vitamins, pregnant women have natural questions: why is it necessary to take the medicine and how safe is it for the unborn baby? In this section, we will talk about medications that are usually prescribed to expectant mothers.

Preparations UTROZHESTAN and DUFASTON are usually prescribed to expectant mothers in the event of such a common problem as the threat of abortion. These drugs contain the hormone progesterone, under the influence of which important biological processes occur in the body of a woman, contributing to the successful bearing of the fetus.

The effect of progesterone on a woman's body is aimed primarily at providing favorable conditions for fertilization, attachment to the wall of the uterus and development gestational sac. The lack of production of this hormone often causes such an unfavorable episode of pregnancy as a miscarriage of the first trimester, because. it was during this period that the fetal egg had not yet attached to the uterus "tightly" and hormonal background mother is not fully formed and stable.

The hormone progesterone refers to progestogens - female sex hormones produced in the ovaries. Even before fertilization, he prepares the uterus for the adoption of the embryo, stimulates the development of the mammary glands. With a lack of progesterone, the mother's body gives the wrong signal immune system, as a result of which the fetus is perceived by the body as a foreign agent, and this leads to detachment of the trophoblast - the “leaf” that feeds the fetus, from which the placenta should subsequently form. As a result, a first trimester miscarriage can occur.

Progesterone began to be used to treat the threat of abortion as early as the 60s and 70s of the last century, but at the same time, its side effects on the child and mother were fully manifested, in particular, fetal malformations could not be avoided. Only with development high technology and the possibilities of using molecular methods of synthesis, it was possible to obtain drugs that can qualitatively and safely deal with this unfavorable moment of pregnancy. These drugs include DUFASTON and UTROZHESTAN.
DUFASTON

DUFASTON is a potent progestogen hormone. which, in its molecular structure and pharmacological action, is close to endogenous (i.e., produced by the body) progesterone and, as a result, has a high affinity for progesterone receptors (structures that perceive the action of this hormone), i.e. fits them perfectly, like a key to a lock.

A "synthetic" change in the configuration of the molecule leads to the fact that DUFASTON is easily absorbed when taken orally. Unlike many progestogen hormones, DUFASTON is not a derivative of the male hormone testosterone - its structure differs from the structure of most synthetic progestogens, as a result of which the drug is devoid of their characteristic side effects. Unlike other synthetic gestagens, DUFASTON:
does not cause the appearance of "female" signs in the male fetus and does not have a side effect on liver function and blood clotting;
does not cause such manifestations as acne, coarsening of the voice, hirsutism (increased hairiness) and masculinization of the genital organs (enlargement of the clitoris) in the female fetus;
does not cause changes in the lipid spectrum of blood and glucose concentration;
does not negatively affect other organs of internal secretion.

The high safety of DUFASTON, confirmed by many years of experience in its use (there was not a single case of detection intrauterine defect development of the fetus), allows you to confidently use the drug as a hormonal support. In addition, compared with UTROZHESTAN, dydrogesterone does not have a sedative (calming) effect. Sometimes this factor contributes to the fact that this drug is chosen for treatment.

Due to the unique correspondence to natural progesterone, DUFASTON recreates the natural mechanisms normal course pregnancy. The results of many studies on this drug are inspiring: the use of DU-FASTON reduces the incidence of placental insufficiency by 2 times, premature birth. And children are less likely to be underweight at birth, get a higher Apgar score (according to this scale, all newborns are evaluated, while paying attention to breathing, heartbeat, reflexes, skin, muscle tone). Newborns are less likely to experience hypoxic (i.e. associated with oxygen starvation) brain damage. Birth frequency healthy children increases by a third.

From side effects to rare cases possible uterine bleeding(In this case, you should immediately consult a doctor). Other side effects this drug was not found.

The only significant contraindication for taking DUFASTON is hypersensitivity to the components of the drug, that is, individual intolerance.

DUFASTON (dydrogesterone) - synthetic analogue natural progesterone, UTROZHESTAN - natural progesterone. This is their main difference, which leads to some differences in the effects and use of these drugs.

Dydrogesterone is secreted from breast milk therefore, if it is necessary to use the drug during lactation, the doctor raises the question of stopping breastfeeding.

DUFASTON is especially often used when using IVF technology - in vitro fertilization. Numerous observations show that the use of a synthetic drug in IVF is more effective than a natural one. natural analogue, although no large international studies have been published on this subject. Long-term use of this drug in a large dose is possible due to the advantages of DUFASTON - high stable availability to tissues and the absence of side effects.
UTROZHESTAN

UTROZHESTAN is the only progesterone in the world produced from vegetable raw materials. This drug is a natural micronized, i.e. produced in special form, progesterone (hormone molecules are surrounded by peanut butter). It is produced in the form of capsules for oral (by mouth) and intravaginal (in suppositories) use.

This drug has a complete resemblance to the progesterone molecule, and it is this property that provides a number of unique effects that distinguish it from other drugs in this group. UTROZHESTAN fully possesses the properties of endogenous (produced in the body) progesterone. It promotes pregnancy, prepares the endometrium for egg implantation. UTROZHESTAN (like DUFASTON) does not change body weight and does not contribute to fluid retention in the body, does not affect lipid and carbohydrate metabolism and does not increase blood pressure.

The unique structure of the UTROZHESTAN molecule allows it to influence the metabolism male hormones androgens (and they are also present in a woman during pregnancy). which not only provides positive impact during pregnancy, but also improves skin condition.

UTROZHESTAN has positive effect and at increased amount in a woman, male sex hormones (hyperandrogenism) due to the fact that this drug interacts in the body with the same receptors as androgens, i.e. competes with them.

Another mechanism unique to UTROZHESTAN for preserving and maintaining pregnancy is its ability to suppress the effects of oxytocin (this hormone is also produced by the ovaries, and it is he who stimulates uterine contractions and leads to miscarriage). This effect of UTROZHESTAN is especially pronounced when taken orally.

The usual dose of UTROZHESTAN is 200-300 mg per day, while any of the two routes of administration of the drug can be used - intravaginal or oral. When eliminating the threat of abortion, the combination of intravaginal administration of UTROZHESTAN with oral administration is more preferable and effective. It is important to note that the initial dose of UTROZHESTAN in case of a threatened miscarriage is 400-600 mg at once, followed by a maintenance dose of 400-600 mg per day. If this therapy is ineffective, the dose of UTROZHESTAN can be increased to 800-1000 mg per day. But the appointment of treatment, as well as changing the dose, should be carried out only by a doctor, since this is a hormonal drug, and its overdose or lack in the body can end tragically for pregnancy. Cancellation of UTROZHESTAN or a change in its dose is carried out under the control of various indicators of pregnancy, including the concentration of progesterone in the blood: it is normal pregnancy changes smoothly - and the cancellation should also occur without "bursts".

Let's say a few words about the side effects that may occur when taking this drug. Like "own" progesterone, UTROZHESTAN slightly increases body temperature and has a calming and hypnotic effect, more pronounced when taken orally. When taking the drug inside, drowsiness and dizziness may also occur.

At serious illnesses oral administration of UTROGEST is contraindicated in the liver - it is recommended to switch to intravaginal use, since the drug is actively metabolized (processed) by the liver.

In conclusion, let me remind dear mothers that if a doctor prescribes to a pregnant woman any of the drugs considered, then this means a complete and serious treatment, since it is associated with the intake of hormones, minimal changes in the concentration of which in the blood (including without the knowledge of the doctor) in one direction or another can cancel out both the doctor's efforts and your pregnancy. Therefore, while taking these medicines, always keep a "hand on the pulse" - visit your doctor regularly and strictly follow his advice.

Pregnancy is the happiest and most best time while waiting for the baby. To realize that a new life is developing inside you, inextricably linked with you - what could be better? Feeling the movements of the baby, talking to him, waiting for him to appear - isn't this the joy of every pregnant woman?

Often expectant mothers are very sensitive and emotional. They are constantly busy with work, because they have so much to do! But not always pregnancy brings only positive feelings.

It happens (and not as rare as we would like) that future mother needed health care in bearing the long-awaited miracle. Feeling unwell women, her chronic diseases, complex unforeseen circumstances - all this affects not only the hormonal background of the pregnant woman, but also the health of her baby.

In such cases, the attending physicians may prescribe drugs such as Utrozhestan or Duphaston. Can they be taken during pregnancy? Of course, there is hardly any woman who would not know about their amazing benefits.

However, many expectant mothers have a completely logical question: what is better during pregnancy - “Utrozhestan” or “Dufaston”? And in general, how do these drugs differ from each other?

To answer the above questions, you must carefully study the instructions for these drugs, as well as analyze them distinctive features. This topic will be the focus of our article.

We will also find out if it is possible to take Utrozhestan and Dufaston at the same time or how to switch from one drug to another. But first, let's discuss the cases in which these drugs are prescribed.

Essential hormone for life

What is the purpose of such a tool as "Utrozhestan" or "Dufaston"? In short, both drugs are artificial substitutes for such important hormone like progesterone. It is part of both products as an active ingredient.

Then in what cases can "Utrozhestan" or "Dufaston" be prescribed?

First of all, when in the body of a woman who wants to become pregnant or is already in interesting position not enough progesterone. How is this hormone different from others?

First of all, progesterone, produced by the ovaries, adrenal glands and placental tissue, prepares the uterine endometrium for the acceptance of a zygote (fertilized egg). It also does not allow the formation of the next eggs (which are no longer necessary) and ensures the full growth and development of the embryo.

As you can see, the presence of the hormone progesterone in required quantity very important for the body of a woman who wants to become a mother. That is why Utrozhestan or Duphaston may be prescribed when planning a pregnancy, especially if the long-awaited fertilization has not occurred for some time.

Having found out why these drugs are needed, let's move on to the analysis of the following important issue. So, which is better: "Utrozhestan" or "Dufaston"? First, let's get acquainted with the instructions for using the first drug.

"Utrozhestan". Composition

First of all, it should be said that this drug is a natural micronized hormone, made on a plant basis. Its structure is very close to the natural progesterone produced by the female body.

Release form of the drug - soft jelly capsules light yellow. In addition to the main active ingredient, the composition of the product includes peanut butter, soy lecithin, glycerol, gelatin, titanium dioxide.

The price of the drug varies in the region of five hundred rubles.

What can be said about when this remedy?

Indications for use

First of all, "Utrozhestan" is prescribed by the attending physician in the presence of such diseases:

• Violations menstrual cycle.
• Infertility caused by pathological contraction of the luteal phase of critical days.
• Menopause, menopause.
• Malfunctions of the ovaries, absence of ovaries.
• Diseases associated with the endometrium.
• Before the IVF procedure.
• The threat of miscarriage or termination of pregnancy.

Mode of application

"Utrozhestan" is available in the form of candles and capsules. Inside, you can take the remedy like this:

• For violations of the menstrual cycle - from two hundred to four hundred milligrams from the 16th to the 26th day, counting from the first day of the onset of menstruation.
• For disorders associated with menopause - two hundred milligrams once a day for twelve days (along with estrogens).

As vaginal suppositories the drug is prescribed in such dosages:

• One hundred to two hundred milligrams twice a day - with the threat of premature birth or miscarriage.
• From two hundred to six hundred milligrams per day during the first four weeks of pregnancy - with artificial insemination.
• Two hundred to three hundred milligrams per day from the 17th to the 27th day of the onset of the menstrual cycle - with infertility.

The exact dosage and schedule for taking the drug is prescribed by the attending physician, taking into account the patient's history and her clinical situation.

"Side"

Side effects when using Utrozhestan are very rare, but you should still be aware of them. First of all, it is:

• Possible violations in the frequency of critical days.
• Discomfort in the mammary glands.
• Vaginal discharge.
• Increased perspiration.
• Increased fatigue, weakness.
• horse racing blood pressure.
• Drowsiness.
• Increased body temperature.
• Bloating, nausea.
• Vertigo.
• Itching of the skin.

Having studied in detail the instructions for the use of "Utrozhestan", let's now carefully read the annotation for "Dufaston".

The composition of "Duphaston"

This tool is an absolutely artificial drug, that is, the structure of progesterone, which is part of it, is completely synthetic, it is slightly different from the natural hormone.

The drug is available in the form of round tablets, coated with a hard shell. white color. The excipients that make up the product are: lactose monohydrate, corn starch, hypromellose, colloidal silicon dioxide, magnesium stearate.

The price of the drug varies in the region of six hundred rubles.

In what cases is this medicine prescribed?

Indications for use

Dydrogesterone (the so-called synthetic progesterone) is prescribed for painful periods, inflammation of the endometrium, infertility, the threat of miscarriage, menopause.

It can also be prescribed by the attending physician during the planning of pregnancy in order to normalize the hormonal background of a woman.

Mode of application

How should the drug be used? "Dufaston" is a tablet remedy, so it can only be used orally:

• Irregular menstrual cycle - ten milligrams twice a day, starting from the eleventh and ending with the 25th day of the cycle.
• Dysmenorrhea, endometrial diseases - ten milligrams two or three times a day from the fifth to the 25th day from the onset of menstruation.
• Infertility - ten milligrams per day from the 14th to the 25th day of the menstrual cycle.
• Threat of miscarriage - one-time forty milligrams, then - ten milligrams every eight hours.
• During menopause and bleeding, a specialist prescribes a specific dosage of the drug.

"Side"

It is very rare, but can cause:

• anemia.
• Headaches.
• Allergic reactions.
• Itching of the skin.
• Minor disturbances in the liver.

Main distinguishing features

After reading the instructions for these drugs, at first glance it may seem that they are identical. And yet there is a difference. It is as follows:

1. First of all, composition. If "Utrozhestan" has completely natural basis, then "Dufaston" is a fully synthetic hormonal drug. In cases where prolonged use of progesterone is justified, Utrozhestan is prescribed as a more natural drug for the female body. If urgent intervention is needed, then they prescribe "Dufaston", which begins to act much faster.
2. Study of the drug. Since Duphaston began to be produced much earlier than Utrozhestan, it is a more studied and clinically tested drug.
3. Possible side effects. "Dufaston", according to reviews, rarely causes unpleasant and unexpected symptoms.
4. Release form. Due to the fact that "Utrozhestan" is available in suppositories for vaginal use, this helps the active substance to be more quickly absorbed in the body and causes fewer side effects.

Combination of drugs in the treatment

Many are interested in whether two hormonal drugs can be taken at the same time? The answer is yes, but only on prescription.

In rare, exceptional cases, a specialist may deem it necessary to prescribe "Utrozhestan" and "Dufaston" together. They may be:

1. Severe lack of progesterone.
2. Threat of miscarriage due to placental abruption.
3. Pregnancy after prolonged infertility.
4. Past pregnancies ended tragically - miscarriages, frozen fetus.
5. Serious gynecological diseases.
6. Anomalies of the uterus.

In such cases, oral administration of "Duphaston" can be supplemented with the use of vaginal suppositories "Utrozhestan".

However, some nuances should be remembered here. Firstly, after the twentieth week of pregnancy, Duphaston is no longer prescribed, since the changes that have occurred in the woman's body during this period make the synthetic hormone ineffective.

Secondly, after the 34th week, pregnant women are strictly forbidden to take progesterone in the form of drugs.

And the most important thing. Only the attending physician should prescribe “Utrozhestan” and “Dufaston” at the same time (in the same way as separately)! A woman should not prescribe medicines for herself, based on her own experience, the recommendations of her friends or information from the Internet.

How to switch from Duphaston to Utrozhestan?

Sometimes this question may also arise. Most often, it is due to the fact that for some reason the drug is not suitable for a woman, or she has the opportunity to purchase Utrozhestan at a discount or even for free. And perhaps by medical indications the doctor independently decides to transfer the patient from one drug to another. Be that as it may, it is possible to take “Utrozhestan” after “Duphaston”, but this must be done under the supervision of a specialist, strictly adhering to the scheme prescribed by him.

A few words in conclusion

Indications for the use of "Utrozhestan" and "Duphaston" are very similar to each other. They can be prescribed for pregnancy planning, infertility, menopause, menstrual irregularities, threatened miscarriage, and the like. Both drugs contain an important active ingredient - the hormone progesterone, which is responsible for the function of conception and gestation of the embryo.

But which is better and more effective - "Utrozhestan" or "Dufaston"? The answer to this question cannot be unambiguous. Only the attending physician has the right to prescribe this or that drug. At the same time, he takes into account not only the composition of each drug and its contraindications, but also the clinical situation of the woman herself, as well as how long the drug will have to be taken.

For example, if you pay attention to the naturalness of the components of the drug, then it is best to use Utrozhestan. If we are talking about an allergic woman, then Duphaston can be prescribed, since it causes a minimum number of side effects. On the other hand, natural progesterone can reduce female body the level of male hormones, while its “competitor” does not have such capabilities.

And yet, we repeat, only a specialist has the right to prescribe this or that hormonal remedy, as well as to prescribe this or that form of release, dosage or schedule of administration. Both drugs are equally effective and have important properties in relation to planning pregnancy, carrying a baby and normalizing the menstrual cycle.

At the threat of interruption. They contain in their composition - the female sex hormone, which is produced in the ovaries. It affects important biological processes in a woman's body, providing conditions for favorable conception and contribute to the successful bearing of the fetus. "Dufaston" and "Utrozhestan" are needed in order to, if necessary, make up for the lack of progesterone and help to deal with adverse moments of pregnancy in a quality and safe manner.

The cancellation of "Duphaston" and "Utrozhestan" or a change in their dose is carried out under the control of various indicators of pregnancy, including the concentration of progesterone in the blood.

What is "Duphaston"

This drug is a potent synthetic analogue of natural progesterone. It is easily absorbed into gastrointestinal tract and has no side effects. "Dufaston" does not have a calming effect, which is sometimes an important factor when choosing a drug. The unique correspondence of "Duphaston" to natural progesterone provides natural mechanism normal course pregnancy.

What are the benefits of "Utrozhestan"

This drug is the only one in the world made from natural raw materials. It fully possesses the properties of the hormone produced in the body. The drug promotes fertilization and prepares the uterus for implantation. An important advantage of "Utrozhestan" is that it is available not only in the form of oral capsules, but also vaginal ones, which is very convenient when a woman is disturbed. However, the drug has some side effects, including fatigue, drowsiness, and worsening mood.

The unique structure of the Utrozhestan molecule ensures the regulation of male sex hormones in a woman's body.

"Duphaston" or "Utrozhestan"?

These do not affect carbohydrate and lipid metabolism and do not contribute to fluid retention in the body, which means that when they are taken, the woman will not get better. In addition, they do not have a contraceptive effect and are not able to negatively affect. According to numerous patient reviews, each drug has its advantages and, but which one is most suitable for a woman, the doctor decides individually. Thanks to Duphaston and Utrozhestan, many of the fair sex have the opportunity to experience the joy of motherhood.

Unfortunately, not all women can easily become pregnant and then bear a child without complications.

Due to strong hormonal changes in the body future mother are happening different kind changes that cause certain problems.

Quite often, in the first weeks of pregnancy, women experience placental abruption, an increased diagnosis, or a miscarriage occurs. The cause of these conditions is the lack of the hormone progesterone. Progesterone belongs to the category of gestagens, the adrenal glands are responsible for its production, corpus luteum ovaries and placental tissues.

At the first signs of a threatened abortion: uterine tone, pulling pains lower abdomen, spotting from the genital tract - progesterone drugs are prescribed, the most popular of which are Duphaston and Utrozhestan.

In our article, we will compare the drugs Utrozhestan and Dufaston, consider their advantages and disadvantages, indications and contraindications for use. Both medications are often prescribed already at the stage of pregnancy planning, since progesterone helps to conceive a baby with problems with its insufficiency.

It has a beneficial effect on the process of attaching the fetal egg to the wall of the uterus and the further bearing of the child, especially at the very beginning of pregnancy, when the immune system can perceive the fetus as a foreign organism and begin to reject it.

These drugs have similar action on the body, their main task is to help a woman become pregnant and maintain a pregnancy. But to find out what better Duphaston or Utrozhestan and how they differ from each other, it is necessary to consider each drug separately.

The composition of Duphaston and Utrozhestan and the release form

These hormonal agents have an identical composition, but their main difference is that Duphaston is a synthetic drug, and Utrozhestan is natural. As part of Utrozhestan, micronized progesterone, obtained from the leaves of the Dioscorea plant and close in formula to the natural one, which is produced by the female body.

Duphaston is artificial analogue progesterone, consists of dydrogesterone, also of plant origin, but subject to a more complex chemical treatment. Utrozhestan is available in two forms: capsules for oral use (orally) and intravaginal suppositories. Duphaston is sold only in the form of tablets.

Indications for the use of Duphaston and Utrozhestan

Both drugs have similar indications to application. Utrozhestan is prescribed with a threat spontaneous interruption pregnancy, mild form, uterine fibroids, hormonal infertility (for example, caused by a cycle), and other gynecological diseases.

Also, the drug is very effective in the presence of women high level male sex hormones. Utrozhestan is a fairly new drug, so in some European countries it is not yet widely used.

Duphaston has been released pharmaceutical industry much earlier than Utrozhestan, and the experience of its use has long history. The artificial configuration of the hormone allows the drug to quickly penetrate the body and be absorbed into the blood at the right concentration.

In addition to being used for threatened miscarriage, Duphaston is also prescribed in preparation for in vitro fertilization, menstrual irregularities, dysfunctional uterine bleeding, replacement therapy after removal of reproductive organs, and infertility.

Conducted studies have shown that Duphaston several times reduces the risk of preterm birth in women who are registered with this problem.

Contraindications to taking Duphaston and Utrozhestan

Since Duphaston is a synthetic analogue of natural progesterone, its use is contraindicated in people with hypersensitivity to its constituents and other components of the drug. Duphaston is also not recommended for women with serious liver diseases (Rotor syndrome, Dubin-Johnson syndrome).

With caution and under the supervision of a physician, Duphaston is prescribed to patients with a history of pruritus during pregnancy. A contraindication to the use of Duphaston is the lactation period, since it penetrates into breast milk.

Utrozhestan, despite its naturalness, has much more contraindications for taking. Utrogestan is not used for bleeding from the genital tract of an unknown nature, if the patient has malignant or reproductive organs, with certain liver diseases (porphyria), during an abortion in progress, with individual intolerance to the components of the drug.

With a tendency to the appearance of blood clots, an intravaginal method of using Utrozhestan is recommended. With caution, this remedy is prescribed to women in the 3rd trimester of pregnancy due to the risk of impaired liver function, as well as during breastfeeding.

Side effects of taking Duphaston and Utrozhestan

When taking Duphaston, the side effects of the patient are practically not noted. The only thing is that occasionally there are breakthrough uterine bleeding, which are eliminated by increasing the dose of the drug.

Utrozhestan has much more side effects, namely: dizziness 30-40 minutes after ingestion, lethargy, drowsiness, mood swings, increased fatigue. Some of them are eliminated by taking Utrozhestan vaginally.

What is better Duphaston or Utrozhestan

It is impossible to unequivocally answer the question of which drug is better than Duphaston or Utrozhestan. Each of them is prescribed by a doctor to a woman, taking into account specific indications, characteristics of the body, focusing on personal experience use or treatment outcomes of other patients.

Both drugs, although hormonal, do not affect body weight, since they do not lead to fluid retention in the body, which is especially important for pregnant women. These drugs do not affect the metabolism, they do not get fat from Duphaston and Utrozhestan.

A big plus is that the drugs also do not lead to an increase in blood pressure. But still both medicines there are pros and cons as well as advantages over each other.

Why Duphaston is better than Utrozhestan:

• few side effects;
• minimal impact on the liver;
• high efficiency in planning a child with the help of IVF (good indicators of fetal survival);
• probability reduction;
• no side effects on the fetus;
• no contraindications to driving while taking Duphaston;
• Duphaston is a more researched drug;
• Duphaston can be taken over long time unlike Urozhestan

Advantages of Utrozhestan:

• a natural drug that is closest in composition to natural progesterone;
• the ability to use the drug both orally and intravaginally (especially method 2 is suitable for pregnant women with strong);
• effective with an excess of male hormones;
• does not provide harmful effects on the fetus;
• low cost of Utrozhestan compared to Duphaston

What drug better fit for you, can only be assessed on own experience. In general, they both do a good job with their functions: they compensate for the deficiency of progesterone in the body, bring the uterus back to normal, eliminating manifestations, reduce the likelihood of miscarriage, and normalize the cycle.

Interchangeability of Duphaston and Utrozhestan

A large number of women are interested not only in the question of which of these means is better, but also whether it is possible to replace Utrozhestan with Dufaston and vice versa. The substitution of one drug for another is different reasons: some patients may have contraindications to taking a particular drug, others may have individual intolerance to the components, others generally just want to receive Duphaston in antenatal clinic free prescription.

It is categorically impossible to prescribe Dufaston or Utrozhestan to yourself, or to replace one remedy with another. Hormonal drugs require strict adherence to instructions and smooth cancellation or transition, therefore, the scheme for switching from Duphaston to Utrozhestan or vice versa for each patient is selected by the doctor individually, taking into account the characteristics of the woman's body, contraindications to taking hormones and pregnancy management.

As a rule, Utrozhestan is usually prescribed to patients in the first trimester (less often in the second) because of the convenience of its use in the form vaginal capsules, especially with severe gestosis of pregnant women. Duphaston can be prescribed at any stage of pregnancy if there is a threat of miscarriage or, according to the results of the analysis, the woman has a clear progesterone deficiency.

How to take Duphaston and Utrozhestan

Duphaston and Utrozhestan regimens for various diseases and pathologies, as well as during pregnancy, are different and are selected individually by a specialist.

To normalize the cycle, Utrozhestan is usually prescribed 200 mg 2 times a day in the morning and evening for 10 days. With the threat of miscarriage during pregnancy, a dose of Utrozhestan is prescribed, equal to 200-600 mg per day. With others pathological conditions the drug is recommended to take from 200 to 400 mg.

The dosage of Duphaston in each case is selected individually. When the cycle is broken and premenstrual syndrome the drug is prescribed 1 tablet 2 times a day for 2 weeks, starting from the 11th day of the cycle, with infertility caused by luteal phase deficiency, Dufaston is drunk from the 14th to the 25th day of the cycle, 1 tablet per day, with threatened abortion prescribe 4 tablets once, then 1 every 8 hours until disappearance anxiety symptoms etc.

In the case of the appointment of progesterone drugs during the planning of a child, a woman often continues to take them for almost the entire pregnancy, since the body is accustomed to the intake of hormones from the external environment and does not cope well with its production in a natural way.

Sometimes the doctor may prescribe the patient the simultaneous use of Duphaston and Utrozhestan in order to minimize the likelihood of developing individual side effects associated with long-term use hormonal drugs. Often, Duphaston is prescribed to a woman orally in addition to the intravaginal use of Utrozhestan.

This reception scheme makes it possible to maintain required level pregnancy hormone progesterone is normal with minimal risk for the expectant mother and fetus. The main thing is to follow the instructions and dosage indicated by the gynecologist.

Cancellation of drugs

On later dates pregnancy, when the placenta is fully formed and is itself able to produce the right amount of progesterone, Duphaston or Utrozhestan are canceled. But in the presence of a prolonged threat of termination of pregnancy, the appearance of pulling pains in the lower abdomen and uterine tone after the abolition of progesterone, Duphaston continues to be taken further.

Utrozhestan is replaced by Duphaston, since it has Negative influence on the liver at the end of the II and III trimesters of pregnancy. The scheme for canceling Duphaston and Utrozhestan is approximately the same - a gradual reduction in the dose of the drug (half a tablet per week or another option proposed by the doctor) with an assessment of the patient's condition.

If Duphaston and Utrozhestan stop taking very abruptly, serious consequences are possible, up to a miscarriage on early term pregnancy and premature birth at a later date. Be careful with taking hormonal drugs and take them only as directed by your doctor.